| ncRNA name | hsa-miR-27a |
| ncRNA Category | miRNA |
| Disease name | uveal melanoma (UM) |
| Species | Homo sapiens |
| Tissues/Cell_line | cutaneous melanoma cell line G361; UM cell line OCM-113; normal human epidermal melanocytes (NHEM) |
| Methods | microarray, qPCR |
| Expression pattern | up-regulated |
| Functional description | Among the 28 miRNAs that were upregulated in both cell lines, only 6 miRNAs had been previously reported to function as oncogenic regulators in melanoma. Sun et al.7 found that genistein altered the expression of miR-27a and its target gene and inhibited human UM cell growth in vitro and in vivo. |
| PubMed ID | 24675509 |
| Year | 2014 |
| Title | Identification of microRNA expression patterns in cutaneous and uveal melanoma cell lines. |
| Drug-related ncRNA | YES (genistein) |
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